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KMID : 0614620090530010029
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Korean Journal of Gastroenterology
2009 Volume.53 No. 1 p.29 ~ p.35
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Clinical Efficacy of Nonsurgical Treatment of Crohn’s Disease-related Intraabdominal Abscess
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Kim Duk-Hwan
Chung Moon-Jae
Han Song-Yi
Cheon Jae-Hee
Park Jae-Jun
Kim Eun-Soo
Kim Tae-Il
Kim Won-Ho
Moon Chang-Mo
Lee Soo-Hyeon
Lee Jin-Ha
Jung Min-Kyu
Son Jung-Woo
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Abstract
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Background/Aims: This study was conducted to compare the clinical efficacy between surgical and nonsurgical treatments for patients with Crohn’s disease-related intraabdominal abscess.
Methods: A retrospective review of medical records was performed for patients admitted to a single institution due to Crohn’s disease-related intraabdominal abscess from February, 1996 to February, 2008. Clinical outcomes were compared between surgical and nonsurgical groups in terms of treatment responses and recurrences.
Results: A total of 47 episodes of intraabdominal abscesses in 43 patients (12.7%) were identified from 339 patients with Crohn’s disease. Of these, initially, 18 cases (38.3%) underwent surgical treatment and 29 (61.7%) were treated medically (antibiotic treatments with or without percutaneous drainage). The overall treatment response rates of surgical and nonsurgical group were 100% versus 89.7% (p=0.11) and recurrence rates were 27.8% versus 30.8% (p=1.00). Three patients in nonsurgical group (10.3%) showed no response to therapy and ultimately received surgical drainages. The median length of hospitalization in nonsurgical group was shorter than in surgical group (12 and 29.5 days, respectively. p=0.02).
Conclusions: Nonsurgical treatment might be as effective as surgical treatment for the treatment of Crohn’s disease-related intraabdominal abscess, especially considering shorter hospital stay.
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KEYWORD
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Crohn’s disease, Inflammatory bowel disease, Abdominal abscess
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